A laboratory built to answer to no one

The institute that tried to abolish the boss

Six decades ago, a charity founded a research center 500 feet from here with no departments and no chain of command.
Last reviewed 19 September 2026 · A four-minute read · 1755–2025
The short answer

Oeiras e São Julião da Barra, Paço de Arcos e Caxias, in Oeiras, Portugal, is home to ground where the Calouste Gulbenkian Foundation built a science institute in 1961 with no departments or chain of command, near the palace grounds of the Marquês de Pombal, who received the land from the crown in 1759.

The institute that tried to abolish the boss — Oeiras
2006 · Vitor Oliveira from Torres Vedras, PORTUGAL · CC BY-S
1961 to 1968

A charity built a science institute with no bosses

The Calouste Gulbenkian Foundation had money meant for the arts. In 1961 its trustees decided to spend some of it on science instead. They wanted a research center with no university rules attached to it. It had to be free of committees and prior claims on what its scientists could study. They built it here, next to the Marquês de Pombal's own palace grounds in Oeiras. The marquess had carved this ground out of the Portuguese crown two centuries earlier.

The Instituto Gulbenkian de Ciência opened its biology center in 1967. It had four small research groups and about twenty scientists. The first years were rough. Between 1966 and 1969, four of the institute's own founding leaders died. They were Delfim Santos, António Gião, Flávio Resende and Luís Quartin Graça. One came from each of the founding centers.

In 1968, a Jesuit priest named Luís Archer came back to Portugal. He set up a molecular genetics laboratory inside the institute's Department of Cell Biology. He is remembered as the father of molecular genetics in Portugal. He built that reputation on this ground. He did it in a lab a charitable foundation had built with no board of governors watching over his shoulder.

A Jesuit priest built Portugal's first molecular genetics lab inside a charity's science institute.
1984 to 2018

Small research groups shared equal footing for decades

In 1984 the foundation's trustees made a decision that set the institute's course for the rest of its life. It would do nothing but biology research and graduate training. This would be permanent. Two more institutes moved onto the same campus in 1989. They were the Instituto de Tecnologia Química e Biológica and the Instituto de Biologia Experimental e Tecnológica.

The bigger change came in 1998, when António Coutinho became director. He had run an immunology unit at the Institut Pasteur in Paris. He rebuilt the institute around small, independent research groups. There was almost no hierarchy between them. Every group got equal access to the same equipment and facilities. This was true whether it was run by a veteran or a scientist just starting out. That structure held. Between 1998 and the institute's final years, 88 research groups worked under it. Researchers from 41 countries passed through its labs.

By 2010 and 2011 the institute was ranked among the ten best places outside the United States for young researchers finishing their doctorates. Mónica Bettencourt-Dias took over as director in February 2018. She was the last person to hold the job under the institute's own name.

In October 2024 the Instituto Gulbenkian de Ciência merged with the Instituto de Medicina Molecular. They became the Gulbenkian Institute of Molecular Medicine. Sixty-three years earlier, a charity built a science institute with no departments and no bosses. It stood on the ground where you are standing. Now it was folded into something else. Its name went with it.

The institute that answered to nobody lasted until 2024, and then it stopped existing.
1759

A marquess ruled this ground on the crown's behalf

In 1759, King Joseph I handed the ground to his minister, the Marquis of Pombal. This was a reward for rebuilding Lisbon. The city had been struck by disaster four years earlier. A royal charter that June gave Pombal jurisdiction over the land. Within a month the village on it became a town, and weeks later a full municipality. Pombal answered to the crown, but on this patch of ground, the crown answered to him. The arrangement did not outlast him by much. Oeiras stopped being its own municipality in 1835, folded back into the ordinary structure of Portuguese local government.

1 November 1755

An earthquake and tsunami struck this stretch of the Tagus

Four years before Pombal's charter, this stretch of the Tagus was struck by catastrophe. An earthquake near magnitude 8.5 to 9.0 hit the Lisbon region on the morning of November 1, 1755. A tsunami followed about forty minutes later, surging up the river past Oeiras. Fires burned for five or six days afterward. Between 60,000 and 100,000 people died in Lisbon and the towns around it. The disaster leveled the old order along with the buildings. It cleared the way for Pombal to remake Lisbon, and to remake this ground as a town that answered only to him.

The next power built here would also be seized, not founded.
1807 to 1831

A fortress built for defence became someone else's barracks

Near Carcavelos, a mile and a half from here, stands the Forte São Julião da Barra. It is the largest Vauban-style fortress in Portugal. It was built to defend the Tagus and answer to no one but the crown that armed it. In November 1807, French troops under General Jean-Andoche Junot occupied it during Napoleon's invasion of Portugal. They turned the fortress into barracks, stripping its original purpose. It stayed a flashpoint. During the Portuguese Civil War, a French fleet under Admiral Albin Roussin bombarded it in 1831. A fortress built to hold its own ground had become someone else's outpost.

2013

Three parishes merged into a single civil parish

Administrative boundaries near the institute went through their own quiet consolidation. In 2013, the parishes of Oeiras e São Julião da Barra, Paço de Arcos and Caxias were merged into a single civil parish. Each of the three had governed its own patch of the coast. After the merger, none of them existed as a separate unit again. The new parish held nearly 34,000 people by the 2011 count, folded together under one name where three had stood before.

The lab where Luís Archer once worked without a boss now carries a different name on the door.

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Where this is

38.686°N 9.322°W TILE ≈ 1.2 × 0.6 KM
Place
Oeiras e Sao Juliao da Barra, Paco de Arcos e Caxias
Town
Oeiras
Country
Portugal
Tile
≈1.2 × 0.6 km (geohash6)
Last reviewed
19 September 2026

The layers, in order

Sourced records, high and medium confidence. Era background is marked as such.
Early modern
November 1, 1755
On November 1, 1755, a massive earthquake shook Lisbon and sent a tsunami surging up the Tagus estuary past this bank around 40 minutes later, part of a disaster that killed tens of thousands.
1759-1835
The land around you was organized as the municipality of Oeiras, Estremadura in 1759, a jurisdiction that lasted until 1835.
FamilySearch Places · record, medium
Modern
1807
In November 1807, Napoleonic troops under General Jean-Andoche Junot occupied the Vauban-style Fort of São Julião da Barra nearby, turning it into barracks.
1831
In 1831, Admiral Albin Roussin's French fleet bombarded the Fort of São Julião da Barra during the Portuguese Civil War.
1835
The municipality was refounded in 1835 under Lisbon district, the jurisdiction that still holds today.
FamilySearch Places · record, medium
1889
The Linha de Cascais railway, with its westbound track passing north of here, opened in 1889 and still connects Lisbon to the coast.
OpenHistoricalMap · record, medium
1961-2024
Founded in 1961 by the Calouste Gulbenkian Foundation, the Instituto Gulbenkian de Ciência became an international center for biological research a short walk away, later merging into the Gulbenkian Institute of Molecular Medicine in 2024.
Wikipedia · record, high
1981
Portuguese actress Elvira Velez, born 1892, died in 1981 and was buried at Oeiras Cemetery about 1.7 kilometers from here.
Wikidata · record, high
installed by 2006
The Parque dos Poetas, photographed here since 2006, includes a statue of poet Alexandre O'Neill, who died in Lisbon in 1986, and one of Sophia de Mello Breyner Andresen by sculptor Francisco Simões.
Wikimedia Commons · record, medium
2011 census
By 2011 the municipality of Oeiras, stretching from this spot toward the coast, held 172,120 people across under 46 square kilometers, one of Portugal's most densely populated municipalities.
Wikipedia · record, high
2013
In 2013, the historic parishes of Oeiras e São Julião da Barra, Paço de Arcos, and Caxias were merged into a single new civil parish covering this ground.
Wikipedia · record, high
March 11, 2025
A head-on collision on Avenida Marginal in Paço de Arcos in March 2025 injured an 11-year-old child, who was treated on the scene, and closed the coastal road.
Notícias de Oeiras · record, medium

Questions about this place

Answered in one sentence, then in full above
What was here before the Instituto Gulbenkian de Ciência was built?
The ground stood near the palace grounds of the Marquês de Pombal, who had been granted this land by King Joseph I in 1759 for rebuilding Lisbon after the earthquake.
What happened at Oeiras during the 1755 Lisbon earthquake?
A tsunami surged up the Tagus past Oeiras roughly forty minutes after the earthquake struck on 1 November 1755, and fires burned for five or six days afterward as part of a disaster that killed between 60,000 and 100,000 people.
Why was the Instituto Gulbenkian de Ciência founded without departments?
The Calouste Gulbenkian Foundation's trustees wanted a research center free of university rules, committees and prior claims on what its scientists could study, opening its biology center in 1967 with four small research groups.
What happened to the Instituto Gulbenkian de Ciência in the end?
In October 2024 it merged with the Instituto de Medicina Molecular to become the Gulbenkian Institute of Molecular Medicine, and its original name ceased to exist.
What happened at the Forte São Julião da Barra?
French troops under General Jean-Andoche Junot occupied the fortress in November 1807 during Napoleon's invasion and turned it into barracks, and in 1831 a French fleet under Admiral Albin Roussin bombarded it during the Portuguese Civil War.
When did the parishes around Oeiras merge?
In 2013, the parishes of Oeiras e São Julião da Barra, Paço de Arcos and Caxias were merged into a single civil parish holding nearly 34,000 people by the 2011 count.

Where this came from

1
Britannica, New World Encyclopedia, and academic sources on seismic history — The 1755 earthquake and tsunami reached this stretch of the Tagus
2
Military Wiki - Fort of São Julião da Barra — French troops occupied the fort at São Julião da Barra
3
FamilySearch Places — Oeiras became its own municipality in 1759
4
FamilySearch Places — Oeiras was reorganized as a municipality of Lisbon district in 1835
5
Wikipedia — The Instituto Gulbenkian de Ciência opened nearby in 1961
6
OpenHistoricalMap — The Cascais railway line's descending track was built past Oeiras in 1889
7
Wikidata — Actress Elvira Velez is buried at Oeiras Cemetery
8
Wikipedia — Oeiras grew into a dense Lisbon suburb by the 21st century
9
Wikimedia Commons — A public sculpture park nearby honors Portuguese poets
10
Wikipedia — The parishes around you merged in 2013
11
Notícias de Oeiras — A collision closed the Marginal at Paço de Arcos in 2025

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